Conference
- Conference Outline
- Program at a glance
- Plenary Lecture
- KSMRM 2021 Symposium
- Downloading e-Abstract
- KSMRM 2021 Workshop
Conference Outline
The 15th Conference of Korean Society for Mitochondrial Research and Medicine
KSMRM 2021 ‘JUMPING!’
Justifying and
Understanding the
Mitochondrial
Platform for Signaling.
Date: 2021.08.25(Wed)
Official language: Korean
Important Dates
Pre-registration Due Date : 2021. 08. 13 (Fri)
Registration Deadline : 2021. 08. 24 (Tue)
Abstract Submission : 2021. 08. 13 (Fri)
How to Submit Abstract
Click the Submitting e-poster
Titles for oral sessions follow
1. Next Generation of Mitochondrial Researchers
2. Technical Advances in Mitochondrial Biology
3. Plenary Lecture by Professor Johan Auwerx
4. Translational Research with Mitochondria
5. Mitochondria as a Clinical Focal Point
Topics of posters include;
Mitochondrial biology: metabolism, biogenesis, electron transport chain, TCA cycle, mitophagy, mitochondrial DNA, organelle communication, proteostasis and quality control, omics, calcium signaling and cell death Mitochondria in medicine: metabolic disease, neurodegenerative disease, genetic disease, preclinical models, biomarkers of disease progression, drugs, molecular therapy
Organized by
Korean Society of Mitochondrial Research and Medicine (KSMRM)
Registration Fee
Regular | ₩ 150,000 |
Student | ₩ 70,000 |
Program at a glance
Wednesday, August 25, 2021 | ||
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09:00 ~ 09:20 |
Registration
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09:20 ~ 09:30 |
Opening Address
Jin Han, President of KSMRM
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Session 1 |
Next Generation of Mitochondrial Researchers
Chair: Myung-Shik Lee (Yonsei University),
Co-Chair: Dongryeol Ryu (Sungkyunkwan University School of Medicine)
Panel: Hyon-Seung Yi (Chungnam National University College of Medicine),
Hyoung Kyu Kim (Inje University College of Medicine),
Jun NAMKUNG (Yonsei University Wonju College of Medicine), Byong Heon Kang (UNIST)
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09:30 ~ 09:50 |
VRK-1 extends life span by activation of AMPK via phosphorylation
Sangsoon Park (KAIST)
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09:50 ~ 10:10 |
Lactation improves pancreatic β cell mass and function through serotonin production
Hyeongseok Kim (Chungnam National University College of Medicine)
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10:10 ~ 10:30 |
Pathological roles of senocules in sync-aging and cardiovascular disorders
Shimizu Ippei (Juntendo University Graduate School of Medicine, Japan)
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10:30 ~ 11:00 |
Coffee Break (+ Poster Viewing)
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Session 2 |
Technical Advances in Mitochondrial Biology
Chair: Jongkyeong Chung (Seoul National University),
Co-Chair: Joo-Yeon Yoo (Pohang University of Science and Technology)
Panel: Kyu-Sang Park (Yonsei University Wonju College of Medicine),
Hyeongseok Kim (Chungnam National University College of Medicine),
Jae Myoung Suh (KAIST), Seung-Jae V. Lee (KAIST)
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11:00 ~ 11:20 |
Monitoring and modeling of single-cell bioenergetics during cell division
Joon Ho Kang (KIST)
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11:20 ~ 11:40 |
In vivo mitochondrial matrix proteome profiling reveals an antioxidant NADPH oxidoreductase
Hyun-Woo Rhee (Seoul National University)
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11:40 ~ 12:00 |
Mitochondrial noncoding RNAs: Function and potential application
Ji Heon Noh (Chungnam National University)
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12:00 ~ 13:30 |
Lunch + CW by Rhino Bio, Inc.
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Session 3 |
Plenary Lecture
Chair: Minho Shong (Chungnam National University School of Medicine)
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13:30 ~ 14:10 |
Cross species genetic mapping of targets in mitochondria and aging
Johan Auwerx Ecole Polytechnique Fédérale Lausanne (EPFL), Switzerland
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Session 4 |
Translational research with mitochondria
Chair: In-Kyu Lee (Kyungpook National University),
Co-Chair: Kyong Soo Park (Seoul National University College of Medicine)
Panel: Chanbae Park (Ajou University), Hail Kim (KAIST),
Joon Won Kang (Chungnam National University College of Medicine),
Jin Han (Inje University College of Medicine)
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14:10 ~ 14:30 |
Interorgan mitochondria stress response regulates thermogenesis
Min Seon Kim (Division of Endocrinology, Department of Internal Medicine,
Asan medical center University of Ulsan College of Medicine)
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14:30 ~ 14:50 |
Role of the mitochondrial stress response in human cancer progression
Young Chan Chae (UNIST)
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14:50 ~ 15:10 |
Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein
Eunna Chung (Cellivery R&D Institute, Cellivery Therapeutics Inc.)
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15:10 ~ 15:40 |
Coffee Break (+ Poster Viewing)
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Session 5 |
Mitochondria as a clinical focal point
Chair: Young-Mock Lee (Yonsei University College of Medicine)
Co-Chair: Jong Hee Chae (Seoul National University College of Medicine)
Panel: Hyun-Wook Chae (Yonsei University College of Medicine),
Ha Neul Lee (Yonsei University College of Medicine),
Ji-Hoon Na (Yonsei University College of Medicine),
Koon Soon Kim (Daejeon Endo Internal Medicine)
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15:40 ~ 16:00 |
Mitochondrial dysfunction in neurological disorders: Structure and functional changes of mitochondria and related organelles in neurotropic factor treated disease model
Ji Young Mun (Korea Brain Research Institute)
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16:00 ~ 16:20 |
Alleviating mitochondrial dysfunction with oral small molecule HSG4112 for the treatment of various diseases
Hyung Soon Park (Director at Research & Development Center of Glaceum Inc.)
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16:20 ~ 16:40 |
Mitochondrial transplantation in Sepsis
Kyuseok Kim (CHA Medical University)
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16:40 ~ 17:00 |
Closing Remarks
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Plenary Lecture
Johan AUWERX
Ecole Polytechnique Fédérale de Lausanne – Swiss Federal Institute of Technology in Lausanne
CURRICULUM VITAE
Abstract
Cross-species genetics and ‘omics to map new players in mitochondria and aging
Our understanding of genetic mechanisms that define complex traits has been hindered by the difficulty of obtaining comprehensive omics datasets across a broad range of biological “layers”. Complete data on the genome of individuals can be readily obtained, but the full complexity of the transcriptome, proteome, metabolome, and phenome have remained largely out of reach. This is, however, beginning to change, with the development of robust multi-layered omics strategies that are pioneered in model organisms. We here profiled the healthspan in >80 cohorts of the BXD mouse genetic reference population. Large variability was observed across all omics layers; to understand how these differences stem from genetic variance, we exploited a multilayered set of molecular phenotypes—genomics, transcriptomics, proteomics, and metabolomics. With this multi-omics strategy, large networks of proteins could be analyzed and causal variants identified in proteins involved in determination of lifespan (e.g. Mrps5, Jmjd3), hypertension (Ubp1) and in mitochondrial metabolism (e.g. Dhtkd1, Cox7a2l). These new candidates were then validated using cross-species genetic strategies in C. elegans, mouse, and human. Our large-scope multi-omics measurements in mouse populations combined with cross-species validation hence provided us with robust conserved and mechanistically defined pathways that underpin complex traits involved in metabolism and aging.
KSMRM 2021 Symposium
KSMRM 2021 SYMPOSIUM | ||
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Session 1 | Next generation of mitochondrial researchers | |
Session 2 | Technical advances in mitochondrial biology | |
Session 3 | Plenary Lecture | |
Session 4 | Translational research with mitochondria | |
Session 5 | Mitochondria as a clinical focal point |
Downloading e-Abstract
12th Symposium of the Mitochondrial Section of KSMCB and KSMRM Workshop
장소 : 울산 UNIST 날짜 : Friday, December 10, 2021
제12차 KSMCB 미토콘드리아분과 학술대회 및 KSMRM 워크샵 | |||
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12:00 ~ 13:10 | Registration | ||
13:10 ~ 13:20 | 한진 | Opening Address (대한미토콘드리아연구의학회장) | |
13:20 ~ 13:30 | 김홍태 | Welcoming Address (울산과학기술원 생명과학과 학과장) | |
Session 1 | Chair | Speaker | Mitochondria in Biology and Medicine |
13:30 ~ 13:43 | 이승재 | 송민호 (5’) | Interactive relationship between creatine metabolism and mitochondrial energy metabolism |
김정태 (8’) | Targeting creatine metabolism slows the development of dextran sulfate sodium induced colitis in mice | ||
13:43 ~ 13:56 | 이현승 (5’) | Effect of salivary exosomal miR-25-3p on periodontitis with insulin resistance | |
전경문 (8’) | Skeletal muscle mitoribosomal defects are linked to bone loss by T cell-mediated bone marrow inflammation | ||
13:56 ~ 14:01 | 박규상 (5’) | Mitochondrial Phosphate Carrier Participates in Vascular Calcification | |
14:01 ~ 14:30 | 강병헌 (5’) | TRAP1 regulation of mitochondrial protein homeostasis | |
김소연 (8’) | Function of mitochondrial HSP90 in tumor micronenvironment | ||
박혜경 (8’) | ROS dependent HIF-1α/CypD negative feedback promotes hypoxia-induced cancer metastasis | ||
윤남구 (8’) | MitoQ inactivates mitochondrial chaperone TRAP1 by interacting with the client binding site | ||
14:30 ~ 15:00 | (30’) | Coffee Break | |
Session 2 | Chair | Speaker | Physiology and Metabolism |
15:00 ~ 15:29 | 강병헌 | 이승재 (5’) | Molecular genetic dissection of aging and immunity |
권수정 (8’) | Male Caenorhabditis elegans exhibit enhanced anti-bacterial immunity via upregulating TFEB/HLH-30 | ||
김시은 (8’) | A ribonuclease that promotes longevity by cleaving age-dependently accumulating circular RNAs | ||
이종선 (8’) | PELO and SKIV2L, key regulators of non-stop decay and no-go decay, are required for preventing cellular senescence | ||
15:29 ~ 15:34 | 김형규 (5’) | Cereblon: Promise and challenges for combating human diseases | |
15:34 ~ 16:11 | 김형석 (5’) | Regulation of cell identity in metabolic organs | |
박정선 (8’) | PAX4 R192H mutation impairs β cell function by affecting endocrine cell differentiation and proliferation | ||
이현규 (8’) | Identifying the mechanism of the loss of cell identity in mouse model | ||
김태강 (8’) | Mitochondrial dysfunction induces loss of beta cell identity | ||
김균후 (8’) | Role of serotonin in beige adipogenesis | ||
16:11 ~ 16:20 | (9’) | Closing Remarks (대한미토콘드리아연구의학회장) |
KOREAN SOCIETY FOR MITOCHONDRIAL RESEARCH AND MEDICINE
KOREAN SOCIETY FOR MITOCHONDRIAL RESEARCH AND MEDICINE
대한미토콘드리아연구의학회
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